You begin taking 1 to 3 gel capsules, morning and evening three days prior to menstruation. When you begin menstruation or when you feel cramping increase, you take 1-3 capsules as need throughout the day. Do not exceed 12 capsules per day. For the most severe days, you may add ibuprofen to Oöna PMS2, albeit it, a lot less.* Menstrual cramps should decrease substantially.*

For more information go to How does Oöna PMS2 work? or How do the herbs work in Oöna PMS1 and OonaPMS2?