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In Oöna, the extracts of both black
cohosh and chaste
tree berry work to normalize hormone production through
the pituitary gland.* Black cohosh appears to address a wide
range of menopausal symptoms, in part by selectively and significantly
reducing levels of luteinizing
hormone (released from the pituitary gland), which often
results in suppression of hot flashes.* Chaste tree berry
is known to work on lowering prolactin
levels,(prolactin is a hormone of the anterior pituitary gland
found in the serum of both normal females and males) which
in turn increases the production of progesterone.*
Low progesterone production is known to be responsible for
many PMS symptoms and menstrual irregularity.*
Scientists believe that the triterpene glycosides
and flavonoids
in black cohosh appear to work together in a myriad of ways,
a belief echoed in the flavonoids of the chaste tree berry.*
Some studies suggest that the compounds in black cohosh bind
to estrogen receptors and mimic the effect of estriol, the
weakest of the three levels of estrogen, one which has never
been associated with increased risk of breast, ovarian or
endometrial
cancers.* And scientists have determined that black cohosh
does not produce an estrogenic effect in target organs of
the uterus or vagina. Additionally, most recent studies concluded
that black cohosh runs interference with neurotransmitters
as its method of working with the body to regulate and thus
alleviate signs of menopause.* It is fairly certain that one
mode of action for chaste tree berry is through neurotransmitters,
interacting with hormone receptors to initiate a reaction
in the pituitary to lower and adjust the production of prolactin.
Both black cohosh and chaste tree berry appear to promote
mild relaxation.* Further, clinical studies show that the
effects of the ingredients in Oöna increase when taken
for the prescribed amount of time, indicating that it encourages
the body to regulate itself and help prevent common symptoms
of menopause from occurring in the first place.* Black cohosh
extract has been studied extensively for 20 years and safely
used by more than one and a half million women in Europe and
Australia. The safety and effectiveness of chaste tree berry
extract has been studied since the 1950s. Now Oöna brings
a delicate yet effective combination of the two extracts to
American women.
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|
|
|
| Increases Risk of Breast Cancer |
No
|
Yes
|
| Increases Risk of Recurrent Endometrial
Cancer |
No
|
Probable
|
| Effective During Perimenopause |
Yes
|
Yes
|
| Effective During Menopause |
Yes
|
Yes
|
| Effective During Post-Menopause |
Yes
|
Yes
|
| Effective for PMS |
Yes
|
Yes
|
| Reduces Hot Flashes |
Yes
|
Yes
|
| Reduces Night Sweats |
Yes
|
Yes
|
| Reduces Sleep Disturbances |
Yes
|
Yes
|
| May Cause Fluid Retention |
No
|
Yes
|
| May Cause Nausea |
No
|
Yes
|
| May Cause Bloating |
No
|
Yes
|
| May Cause Headache |
No
|
Yes
|
| May Cause Weight Gain |
No
|
Yes
|
| Increases Irritability |
No
|
Probable
|
| Decreases Irritability |
Yes
|
No
|
| All Natural |
Yes
|
No
|
Sources:
1.Murray, N.D. Michael T. Hormone
Replacement Therapy vs. Black Cohosh in Menopause.
Encyclopedia of Nutritional Supplements. Prima Publishing,
1996.
2. Schellenberg, R. Treatment for the
premenstrual syndrome with agnus castus fruit extract: prospective,
randomized, placebo controlled study. British Medical Journal
2001; 322:134-137 Jan 20.
3. Foster, Steven. Black Cohosh: Cimicifuga
racemosa: a literature review. Herbal
Gram 45. Winter 1999.
4. ACOG Committee on Practice Bulletins—Gynecology
and Taylor, M.D. Maida. Use of Botanicals for Management
of Menopausal Symptoms. ACOG Practice Bulletin Number 28,
June 2001.
5. Creasman WT. Is there an association
between hormone replacement therapy and breast cancer? J
Women’s Health 1998:7:1231-1246.
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